Early stage cherry eye in dogs
The early stage cherry eye in dogs is also called the cherry eye, cherry pupil, or early-stage nuclear sclerosis.
It is also known as posterior staphyloma (staphyloma of the posterior pole). This condition results from a posterior protrusion of the iris into the angle. When the iris bulges into the angle, the angle is narrow. As a result, there is increased pressure on the back of the eye, which can lead to glaucoma.
Cherry eye in dogs is most often seen in older, adult dogs and has a genetic basis. It is seen in several breeds.
Signs and symptoms
Cherry eye is a medical term that describes a visible eye condition that is present at birth. It is also known as "doggie eyes". The affected eye appears as a "cherry" with black or purple iris. As a result, the black portion of the eye appears "inflamed" and swollen.
Although the affected eye appears to be normal when seen from the front, a dog with early stage cherry eye has a bulging iris. As a result, the iris protrudes into the angle of the eye (posterior staphyloma). When this occurs, the angle is narrow, which causes increased pressure on the back of the eye. This can lead to glaucoma, blindness, and other eye problems.
The condition is most common in older, adult dogs. A dog can have cherry eye as a result of being born with it or having it develop later in life.
Cherry eye is a hereditary condition and may have a genetic basis. The condition is also present in a number of breeds and can occur as a result of other eye diseases.
The condition can be present at birth or may develop later in life. A study found that early stage cherry eye is hereditary in Irish setters, German shepherds, miniature pinschers, cocker spaniels, golden retrievers, and French bulldogs.
A genetic basis
Cherry eye is a condition of iris atrophy. Iris atrophy is a condition where the color of the iris (the circular pigmented epithelium of the iris) becomes less visible because of damage to the iris pigment epithelium. The most common cause of iris atrophy is a condition called glaucoma.
Glaucoma is caused by an increase in intraocular pressure (IOP). Glaucoma is an increase in the pressure of fluid (fluid) in the eye. The pressure of the fluid may be higher than is normal. The increased pressure can lead to vision problems. Glaucoma may cause damage to the optic nerve (cranial nerve III), which leads to vision loss.
In glaucoma, the pressure of fluid is caused by an excess of fluid around the iris (uvea). This excess fluid can increase the size of the iris. The condition leads to an enlargement of the iris or an increased size of the iris.
A study found that early stage cherry eye has a genetic basis in Irish setters, miniature pinschers, German shepherds, and cocker spaniels. The study found that dogs with the condition were carriers of a mutation in the PAX6 gene. Mutations in the PAX6 gene are the cause of several eye diseases, including aniridia (absence of the iris). The iris is an eye organ that is located in the front part of the eye.
The study found that affected dogs were heterozygous carriers of the mutation, which means they had inherited one mutated gene and one normal gene from their parents. The heterozygous dogs had early stage cherry eye but were not blind or had vision problems. The study suggested that other eye diseases may be present when the condition occurs. It also noted that dogs with the condition had a normal iris.
Aniridia (absence of the iris) is another condition in which there is no iris in the eye. Aniridia may have a genetic basis, but may also be present at birth as a result of trauma. Aniridia may cause blindness.
Another study found that early stage cherry eye was present in several breeds: Irish setters, French bulldogs, cocker spaniels, golden retrievers, and Yorkshire terriers.
Cherry eye that develops as a result of trauma
Cherry eye can be present at birth or it may develop later in life. A condition called iridocorneal endothelial syndrome (ICE syndrome) is most often present when cherry eye develops at birth.
ICE syndrome is a condition in which there is damage to the endothelium of the iris (innermost layer of the iris). The endothelium serves as a barrier between the aqueous humor in the anterior part of the eye and the iris.
The condition is most often caused by trauma to the eye (a condition called iridocorneal endothelial dystrophy, also known as Fuch's dystrophy or pseudoglioma).
An injury to the eye can cause damage to the endothelium of the iris. The condition can also be caused by inflammation of the iris or by exposure to smoke, r pollution, and other toxins.
A condition called iris neovascularization, or angioma, is also present in dogs with early stage cherry eye. Iris neovascularization is the development of blood vessels in the iris. The condition may be caused by an injury to the iris or by another disease. In dogs, the condition is most often caused by iris neovascularization that develops as a result of an injury to the eye. The condition is usually found in older, adult dogs.
An injury to the eye may also cause damage to the pigment epithelium (outermost layer of the iris). As a result of this damage, the pigment epithelium may not produce as much pigment as it should.
A study found that